Bivalirudin

Bivalirudin Structure

Name: Bivalirudin; Angiomax; BG-8967; Bivalirudin Trifluoroacetate
CAS No.: 128270-60-0
Peptide Sequence: DPhe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-lle-Pro-Glu-Glu-Tyr-Leu
Molecular Formula: C98H138N24O33
Molecular Weight: 2180.29
Appearance: White Lyophilized powder

Bivalirudin reversibly binds thrombin, free as well as clot bound, at the catalytic site and the anion-binding exosite, thereby preventing the formation and activation of fibrin, factor XIIIa, and other coagulation factors. This drug is primarily used during coronary angioplasty procedures, in combination with aspirin, in patients with unstable angina.