HGH
20/12/2021 2021-12-20 10:31HGH
The benefits, facts and fictions of human growth hormone
Can human growth hormone really promote aging like the elusive fountain of youth? In 1513, Spanish explorer Juan Ponce de Leon (Juan Ponce de Leon) arrived in Florida in search of the Fountain of Youth. If he gets any benefit from his exploration, it is due to the exercises involved in the search.
Few people today believe in miracle water, but it seems that many people believe in the syringe of youth. They do not drink rejuvenating water, but inject human growth hormone to slow the ticking of the clock. Some are motivated by the proposition of “anti-aging” sports, while others are motivated by examples of young athletes seeking a competitive advantage. Like Ponce de Len, athletes can still benefit from exercise, and older men may use growth hormone instead of exercise. But will growth hormone improve performance or delay aging? Is it safe?
What is HGH?
Growth hormone (GH) or growth hormone, also known as human growth hormone (hGH or HGH), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. Therefore, it is very important in human development. GH also stimulates the production of IGF-1 and increases the concentration of glucose and free fatty acids. It is a mitogen, which is specific only for receptors on certain types of cells. GH is a single-chain polypeptide of 191 amino acids, synthesized, stored and secreted by growth-promoting cells in the anterior pituitary flanks.
A recombinant hGH called growth hormone (INN) is used as a prescription medicine to treat growth disorders in children and growth hormone deficiency in adults. In the United States, it can only be obtained legally from a pharmacy through a prescription from a licensed healthcare provider. In the United States in recent years, some healthcare providers are prescribing growth hormone for the elderly to increase vitality. Although legal, the effectiveness and safety of this use for HGH have not been tested in clinical trials. Many functions of hGH are still unknown.
As an anabolic agent, HGH has been used by athletes in sports since at least 1982 and has been banned by the International Olympic Committee and NCAA. Traditional urinalysis cannot detect HGH stimulants, so the ban was not implemented until the early 2000s, when blood tests to distinguish between natural and artificial HGH began to develop. The blood test conducted by WADA at the 2004 Olympic Games in Athens, Greece was mainly for HGH. Currently, the FDA has not approved the drug for performance enhancement.
GH has been studied to be used to raise livestock more efficiently in industrialized agriculture, and some efforts have been made to obtain government approval for the use of GH in livestock production. These uses have always been controversial. In the United States, the only GH approved by the FDA for use in livestock is the use of a cow-specific form of GH called bovine growth hormone to increase milk production in dairy cows. Retailers can put labels on milk containers with or without bovine growth hormone.
Benefits
Adults with growth hormone deficiency—rather than the expected decline in growth hormone due to aging—may be prescribed synthetic HGH by their healthcare provider.
Growth hormone deficiency is usually caused by a benign tumor on the pituitary gland (pituitary adenoma) or treatment of adenoma by surgery or radiotherapy.
For adults with growth hormone deficiency, HGH injection can:
Increase athletic ability
Increase bone density
Increase muscle mass
Reduce body fat
HGH therapy is also approved for the treatment of adults with AIDS or HIV-related growth hormone deficiency, which causes irregular distribution of body fat.
Medical use
Replacement therapy
GH is used as an alternative therapy for adults with GH deficiency in childhood or adulthood (usually as a result of acquired pituitary tumors). In these patients, benefits include reduced fat mass, increased lean body mass, increased bone density, improved blood lipids, reduced cardiovascular risk factors, and improved social and mental health.
Other approved uses
GH can be used to treat diseases that cause short stature but are not related to GH deficiency. However, compared to the short stature that is entirely due to the lack of GH, the results are less dramatic. Examples of other causes of short stature that are often treated with GH include Turner syndrome, chronic renal failure, Prader-Willi syndrome, intrauterine growth restriction, and severe idiopathic short stature. In these cases, higher doses are required to significantly accelerate growth, resulting in blood levels much higher than normal.
A version of rHGH has also been approved by the FDA to maintain muscle mass lost due to AIDS.
Side effects
Injection site reactions are common. More rarely, patients experience increased risk of joint swelling, joint pain, carpal tunnel syndrome, and diabetes. In some cases, patients can develop an immune response against GH. GH may also be a risk factor for Hodgkin’s lymphoma.
A survey of adults who received alternative cadaveric GH treatment during childhood (not used anywhere in the world since 1985) showed a slight increase in the incidence of colon cancer and prostate cancer, but the link with GH treatment not sure yet.